Disease encyclopedia/Lungs & airways
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    Lungs & airwaysCancerICD-10 C45

    Mesothelioma

    A cancer of the pleura (the lining around the lungs) almost always caused by asbestos exposure decades earlier.

    Condition-specific references are below. Individual claims and this page have not been clinically reviewed. Read about this content.

    Affected: Pleura

    Causes

    • Asbestos fibre exposure

    Risk factors

    • Work in construction, shipbuilding, insulation or demolition
    • Household exposure from a worker's clothes

    Symptoms

    • Chest pain
    • Breathlessness from pleural effusion
    • Weight loss
    • Sweats

    Diagnosis — tests and examinations

    • CT scan
    • Pleural fluid cytology
    • Thoracoscopic biopsy

    Treatment

    Medicines and medical treatment

    • Immunotherapy (nivolumab plus ipilimumab)
    • Chemotherapy (platinum and pemetrexed)
    • Radiotherapy for pain

    Operations and procedures

    • Pleural drainage and pleurodesis
    • Surgery in selected patients

    Self-care, home remedies and lifestyle

    • Palliative care support
    • Seek compensation advice for occupational exposure

    Possible complications

    • Pleural effusion
    • Chest wall invasion

    Prevention

    • Asbestos safety regulations and protective equipment

    Outlook

    Generally poor; median survival about 1–2 years, improving with immunotherapy.

    When to see a doctor

    See a doctor for chest pain or breathlessness if you have past asbestos exposure.

    Sources and further reading

    These sources cover this condition. They have not been checked against every statement on this page.

    • Mesothelioma — MedlinePlus (U.S. National Library of Medicine)

    Related conditions

    Pneumothorax (collapsed lung)Pleural effusionAsthmaChronic obstructive pulmonary diseasePneumoniaLung cancer

    Educational overview, not medical advice. Treatment varies by person and location. Consult a qualified health professional for diagnosis or care. Read our content and model notes and privacy information.

    Affected: Pleura

    See it in 3-D

    Right lung — inferior lobe

    Anatomy

    • Right lung — inferior lobe

    On this page

    • Causes
    • Risk factors
    • Symptoms
    • Diagnosis — tests and examinations
    • Treatment
    • Complications
    • Prevention
    • Outlook
    • When to see a doctor
    • Sources