Disease encyclopedia/Brain & nerves
    3-D atlas
    Brain & nervesAcute vascular eventICD-10 I63 / I61

    Stroke

    Also called: Cerebrovascular accident, CVA, Brain attack, Ischaemic stroke, Haemorrhagic stroke

    This can be a medical emergency. Call emergency services immediately for any sudden face drooping, arm weakness or speech difficulty — even if it goes away (TIA).

    Blood supply to part of the brain is suddenly cut off by a clot (ischaemic, about 85%) or a burst blood vessel (haemorrhagic). Brain cells die within minutes, so fast treatment saves brain function — 'time is brain'.

    Condition-specific references are below. Individual claims and this page have not been clinically reviewed. Read about this content.

    About 12 million strokes a year worldwide; the second leading cause of death and a leading cause of disability.

    Affected: Brain, Cerebral arteries

    What happens in the body

    In ischaemic stroke a clot from the heart (atrial fibrillation), a carotid plaque or small-vessel disease blocks an artery; a core of tissue dies while a surrounding 'penumbra' can still be rescued. In haemorrhagic stroke bleeding raises pressure and damages tissue directly.

    Causes

    • Clots from the heart, especially atrial fibrillation
    • Atherosclerosis of carotid or brain arteries
    • Small-vessel disease from hypertension and diabetes
    • Bleeding from hypertensive vessels, aneurysms or malformations
    • Arterial dissection in younger people

    Risk factors

    • High blood pressure (most important)
    • Atrial fibrillation
    • Smoking
    • Diabetes
    • High cholesterol
    • Obesity and inactivity
    • Excess alcohol
    • Previous stroke or TIA
    • Age

    Symptoms

    • BE FAST: Balance loss, Eyes (vision loss), Face drooping, Arm or leg weakness, Speech difficulty — Time to call emergency services
    • Sudden numbness on one side
    • Sudden confusion or trouble understanding
    • Sudden severe headache (haemorrhage)

    Diagnosis — tests and examinations

    • Emergency CT scan to exclude bleeding
    • CT angiography and perfusion to find a blocked artery
    • MRI
    • ECG and heart monitoring for atrial fibrillation
    • Carotid ultrasound, echocardiography, blood tests

    Treatment

    Medicines and medical treatment

    • Clot-busting drugs (alteplase or tenecteplase) within 4.5 hours of onset
    • Aspirin after bleeding is excluded
    • Stroke unit care (swallowing assessment, positioning, early mobilisation)
    • Blood-pressure lowering and reversal of anticoagulants in haemorrhage
    • Secondary prevention: antiplatelets or anticoagulants for AF, statins, blood-pressure control

    Operations and procedures

    • Mechanical thrombectomy for large-vessel blockage, up to 24 hours in selected patients
    • Carotid endarterectomy or stenting for significant carotid narrowing
    • Neurosurgery for some brain haemorrhages; aneurysm coiling or clipping

    Self-care, home remedies and lifestyle

    • Rehabilitation: physiotherapy, occupational and speech therapy
    • Stop smoking, control blood pressure, healthy diet, exercise
    • Take preventive medicines every day

    Possible complications

    • Paralysis and loss of function
    • Speech and swallowing problems
    • Aspiration pneumonia
    • Depression
    • Epilepsy
    • Vascular dementia
    • Recurrent stroke

    Prevention

    • Control blood pressure
    • Anticoagulation for atrial fibrillation
    • Not smoking, healthy weight, exercise, moderate alcohol

    Outlook

    Varies widely; many recover substantially with rapid treatment and rehabilitation, but about a third are left with lasting disability.

    When to see a doctor

    Call emergency services immediately for any sudden face drooping, arm weakness or speech difficulty — even if it goes away (TIA).

    Sources and further reading

    These sources cover this condition. They have not been checked against every statement on this page.

    • Stroke — MedlinePlus (U.S. National Library of Medicine)

    Related conditions

    Subarachnoid haemorrhageTransient ischaemic attack (mini-stroke)MigraineEpilepsyAlzheimer's diseaseMultiple sclerosis

    Educational overview, not medical advice. Treatment varies by person and location. Consult a qualified health professional for diagnosis or care. Read our content and model notes and privacy information.

    Affected: Brain, Cerebral arteries

    See it in 3-D

    Left cerebral hemisphereRight cerebral hemisphereCommon carotid artery (left)

    Anatomy

    • Left cerebral hemisphere
    • Right cerebral hemisphere
    • Common carotid artery

    On this page

    • What happens in the body
    • Causes
    • Risk factors
    • Symptoms
    • Diagnosis — tests and examinations
    • Treatment
    • Complications
    • Prevention
    • Outlook
    • When to see a doctor
    • Sources